Caspase 1 (ICE) Substrate 2f, fluorogenic | DNA

Product Name :
Caspase 1 (ICE) Substrate 2f, fluorogenic

CAS NO. :
219137-85-6

Formula :
C33H36O10N4F3

Molecular Weight::
705.65

Target:
Fluorescent Dye

Serial Number:
Ac-Tyr-Val-Ala-Asp-AFC

Short serial number :
Ac-YVAD-AFC

Purity:
95%

Description :
The presence of halogen substituents at the fluorescent group improves membrane permeability of the YVAD-derived caspase-1 substrate.

References:
[1]. Furuoka M, et al. TNF-α Induces Caspase-1 Activation Independently of Simultaneously Induced NLRP3 in 3T3-L1 Cells. J Cell Physiol. 2016 Dec;231(12):2761-7. [2]. Guo RF, et al. Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis. J Clin Invest. 2000 Nov;106(10):1271-80.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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