Product Name :
Tyrosine Protein Kinase Substrate
CAS NO. :
81493-98-3
Formula :
C66H109N23O23
Molecular Weight::
1592.71
Target:
others
Serial Number:
Arg-Arg-Leu-Ile-Glu-Asp-Asn-Glu-Tyr-Thr-Ala-Arg-Gly-OH
Short serial number :
RRLIEDNEYTARG
Purity:
95%
Description :
The sequence RLIEDNEYTARG corresponds to the sequence of the reported site of tyrosine phosphorylation (i.e. amino acids 412-422) in the Rous sarcoma virus-encoded transforming protein pp60 src. In vitro tyrosine phosphorylation of the peptide is stimulated by epidermal growth factor.
References:
[1]. Ohguro H, et al. Separation of phospho- and non-phosphopeptides using reverse phase column chromatography. FEBS Lett. 1995 Jul 24;368(3):452-4. [2]. Ernould AP, et al. Purification and characterization of the major tyrosine protein kinase from the human promyelocytic cell line, HL60. Eur J Biochem. 1993 Jun 1;214(2):503-14. [3]. L J Pike, B Gallis, et al. Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes. Proc Natl Acad Sci U S A. 1982 Mar;79(5):1443-7.
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