β-Amyloid/A4 Protein Precursor (APP) (96-110), analog

Product Name :
β-Amyloid/A4 Protein Precursor (APP) (96-110), analog

CAS NO. :

Formula :
C81H128N32O19S2

Molecular Weight::
1918.25

Target:
Amyloid-β

Serial Number:
Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2 (Disulfide bridges:Cys98-Cys105 )

Short serial number :
Ac-NWCKRKQCKTHPH-NH2(Disulfide bridges:Cys98-Cys105 )

Purity:
≥95%

Description :
Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.

References:
[1].D.H. Small et al., J. Neurosci.,14,2117 （1994）

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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