Product Name: Canertinib
Chemical Name: N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide
SMILES Code: C=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
CAS NO: 1082948-81-9 Product: GSK2110183 (hydrochloride)
Synonym: CI-1033; PD-183805; CI1033; CI 1033; PD183805; PD 183805
Chemical Formula: C24H27Cl3FN5O3
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).GSNOR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Canertinib (CI-1033, PD183805) is an irreversible quinazoline-based inhibitor of HER family tyrosine kinases with IC50 values of 0.8, 19 and 7 nM for EGFR, HER2 and HER4, respectively. Canertinib irreversibly binds into the ATP pocket within the TK domainPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20410884
