MMP-13, Substrate | DNA_ Alkylatingdna-alkylating.com

Product Name :
MMP-13, Substrate

CAS NO. :
1872435-02-3

Formula :
C40H64N14O12S1

Molecular Weight::
965.09

Target:
MMP

Serial Number:
Dnp-Gly-Pro-Leu-Gly-Met-Arg-Gly-Leu-NH2

Short serial number :
Dnp-GPLGMRGL-NH2

Purity:
95%

Description :
Highly sensitive and selective substrate for collagenase-3 (MMP-13) with a kcat/Km value of 4.22 · 10⁶ M⁻¹s⁻¹ (pH = 7.5, T = 37 °C). The kcat/Km value of human collagenase-3 for this synthetic peptide is 1344-, 11-, and 820-fold better than that of related MMPs stromelysin-1 (MMP-3), gelatinase B (MMP-9), and collagenase-1 (MMP-1), respectively.

References:
[1]. Hu Q, Ecker M. Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis. Int J Mol Sci. 2021 Feb 9;22(4):1742.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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