Product Name: Jasplakinolide
Chemical Name: (3S,6R,9R,13S,15R,16E,19S)-3,5,13,15,17,19-Hexamethyl-6-[(2-bromo-1H-indole-3-yl)methyl]-9-(4-hydroxyphenyl)-12-oxa-2,5,8-triazacyclononadeca-16-ene-1,4,7,11-tetraone
SMILES Code: C/C(C[C@H](C)C(N[C@@H](C)C(N(C)[C@H](CC1=C(Br)NC2=C1C=CC=C2)C(N[C@@H](C3=CC=C(O)C=C3)C4)=O)=O)=O)=C[C@H](C)C[C@H](C)OC4=O
CAS NO: 85175-67-3 Product: Acetazolamide
Synonym: NSC 613009
Chemical Formula: C36H45BrN4O6
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Dipeptidyl Peptidase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Jasplakinolide (NSC 613009) is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actiPubMed ID:http://molpharm.aspetjournals.org/content/57/5/976.full.pdf
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Product Name: Jasplakinolide
Chemical Name: cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-8S-hydroxy-2S,4E,6R-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]
SMILES Code: C/C(C[C@H](C)C(N[C@@H](C)C(N(C)[C@H](CC1=C(Br)NC2=C1C=CC=C2)C(N[C@@H](C3=CC=C(O)C=C3)C4)=O)=O)=O)=C[C@H](C)C[C@H](C)OC4=O
CAS NO: 1355326-21-4 Product: K-Ras G12C-IN-1
Synonym: NSC 613009
Chemical Formula: C36H45BrN4O6
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Renin inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Jasplakinolide (NSC 613009) is a natural macrocyclic peptide first isolated from a marine sponge. It potently inhibits the proliferation of PC3 prostate carcinoma cells (IC50 = 35 nM) by binding F-actin (KD = 15 nM). This binding of jasplakinolide to actiPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10952482