Product Name: GDC-0917
Chemical Name: (S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-N-(2-(oxazol-2-yl)-4-phenylthiazol-5-yl)pyrrolidine-2-carboxamide
SMILES Code: O=C([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)CCC1)NC3=C(C4=CC=CC=C4)N=C(C5=NC=CO5)S3
CAS NO: 70578-24-4 Product: SAR407899 (hydrochloride)
Synonym: GDC0917; GDC 0917; CUDC427; CUDC-427; CUDC 427
Chemical Formula: C29H36N6O4S
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).DGAT inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GDC-0917 (CUDC-427) is an orally available, monovalent mimetic of second mitochondrial-derived activator of caspases and inhibitor of IAPs (Inhibitor of Apoptosis Proteins) with potential antineoplastic activity. Smac mimetic CUDC-427 binds to the Smac biPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20565110