Product Name: G-5555
Chemical Name: 8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
SMILES Code: CNC1=NC=C2C(N(C[C@H]3OC[C@H](N)CO3)C(C(C4=CC=C(C5=CC=CC(C)=N5)C=C4Cl)=C2)=O)=N1
CAS NO: 73870-35-6 Product: SAR407899
Synonym: G5555; G 5555
Chemical Formula: C25H25ClN6O3
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Cytochrome P450 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: G-5555 is a selective PAK1 Inhibitor (Ki=3.7 nM). MetonChem offers G-5555 with high quality at great price. G-5555 is potent, showing good activity in the pMEK cellular assay (IC50=69 nM), has improved permeability, and importantly, displayed low hERG chaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21077691
