Product Name: AR-11324
Chemical Name: (S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate
SMILES Code: CNC1=NC=C2C(N(C[C@H]3OC[C@H](N)CO3)C(C(C4=CC=C(C5=CC=CC(C)=N5)C=C4Cl)=C2)=O)=N1
CAS NO: 96020-91-6 Product: EX-527 (S-enantiomer)
Synonym: AR 11324; AR11324; Netarsudil
Chemical Formula: C28H27N3O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).COMT inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AR-11324 (Netarsudil) is a Rho-associated protein kinase inhibitor. AR-11324 is potential useful for treating glaucoma and/or reducing intraocular pressure. Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of sePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20461084
