Product Name :
GRGDSPK
CAS NO. :
111119-28-9
Formula :
C28H49N11O11
Molecular Weight::
715.76
Target:
Integrin
Serial Number:
Gly-Arg-Gly-Asp-Ser-Pro-Lys
Short serial number :
GRGDSPK
Purity:
95%
Description :
GRGDSPK TFA (EMD 56574 TFA) is a peptide containing arginine-glycine-aspartic acid (RGD). GRGDSPK TFA is a competitive and reversible inhibitory peptide that inhibits integrin-fibronectin binding. GRGDSPK TFA can be used to study the role of integrins in bone formation and resorption.
References:
[1]. G A Gronowicz, et al. Synthetic Peptide Containing Arg-Gly-Asp Inhibits Bone Formation and Resorption in a Mineralizing Organ Culture System of Fetal Rat Parietal Bones. J Bone Miner Res. 1994 Feb;9(2):193-201. [2]. Pierre-Henri Puech, et al. Measuring Cell Adhesion Forces of Primary Gastrulating Cells From Zebrafish Using Atomic Force Microscopy. J Cell Sci. 2005 Sep 15;118(Pt 18):4199-206. [3]. Sessions BR, et al. Effects of amino acid substitutions in and around the arginine-glycine-aspartic acid (RGD) sequence on fertilization and parthenogenetic development in mature bovine oocytes. Mol Reprod Dev. 2006 May;73(5):651-7.
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