Product Name :
Proadrenomedullin (1-20) (human)
CAS NO. :
150238-87-2
Formula :
C112H178N36O27
Molecular Weight::
2460.87
Target:
others
Serial Number:
Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2
Short serial number :
ARLDVASEFRKKWNKWALSR-NH2
Purity:
≥95%
Description :
Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release–inhibitory peptide released from chromaffin cells with an IC50 of ~350 nM for catecholamine secretion in PC12 pheochromocytoma cells, acting in a noncompetitive manner specifically at the nicotinic cholinergic receptor.
References:
[1]. Mahata M, et al. Proadrenomedullin N-terminal 20 peptide: minimal active region to regulate nicotinic receptors. Hypertension. 1998 Nov;32(5):907-16.
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