Product Name: PF-3644022
Chemical Name: (R)-10-methyl-3-(6-methylpyridin-3-yl)-11,12-dihydro-10H-[1,4]diazepino[5′,6′:4,5]thieno[3,2-f]quinolin-8-ol
SMILES Code: CC1=NC=C(C2=NC(C=CC(S3)=C4C5=C3C(O)=N[C@](CN5)([H])C)=C4C=C2)C=C1
CAS NO: 1049731-36-3 Product: GV-58
Synonym: PF 3644022; PF3644022
Chemical Formula: C21H18N4OS
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).SGLT inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PF-3644022 is a potent and selective mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) inhibitor (Ki =3 nM). PF-3644022 is the first oral MK2 inhibitor in both acute and chronic models of inflammation. PF-3644022 reversibly ATP-compPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/12379227
