Product Name: GDC-0425
Chemical Name: 5-((1-ethylpiperidin-4-yl)oxy)-9H-pyrrolo[2,3-b:5,4-c’]dipyridine-6-carbonitrile
SMILES Code: N#CC1=NC=C2C(C3=CC=CN=C3N2)=C1OC4CCN(CC)CC4
CAS NO: 1321546-70-6 Product: LDC1267
Synonym: GDC0425; GDC 0425; RG7602; RG-7602; RG 7602
Chemical Formula: C18H19N5O
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).nAChR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GDC-0425 (RG7602) is an oral, selective Chk1 inhibitor. GDC-0425 enhances gemcitabine (gem) efficacy in tumor xenograft models. Greater chemopotentiation is observed in cancer cell lines lacking p53 activity. GDC-0425 blocks the function of a protein callPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20589168
