Product Name :
2-Furoyl-LIGRLO-amide
CAS NO. :
729589-58-6
Formula :
C36H63O8N11
Molecular Weight::
777.95
Target:
Protease Activated Receptor (PAR)
Serial Number:
2Furanylcarbonyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2
Short serial number :
2Fur-LIGRLO-NH2
Purity:
95%
Description :
2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.
References:
[1]. McGuire JJ, et al. 2-furoyl-LIGRLO-amide: a potent and selective proteinase-activated receptor 2 agonist. J Pharmacol Exp Ther. 2004 Jun;309(3):1124-31. [2]. Lohman RJ, et al. An antagonist of human protease activated receptor-2 attenuates PAR2 signaling, macrophage activation, mast cell degranulation, and collagen-induced arthritis in rats. FASEB J. 2012 Jul;26(7):2877-87. [3]. Jiahui Zhao, et al. PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes. J Invest Dermatol
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