Product Name :
Calcium-Like Peptide 3
CAS NO. :
261969-05-5
Formula :
C44H68N10O9
Molecular Weight::
881.07
Target:
Calcium Channel
Serial Number:
Val-Lys-Phe-Gly-Val-Gly-Phe-Lys
Short serial number :
VKFGVGFK
Purity:
95%
Description :
CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia.
References:
[1].A new type of Ca(2+) channel blocker that targets Ca(2+) sensors and prevents Ca(2+)-mediated apoptosis. [2]. BH3 mimetic-elicited Ca 2+ signals in pancreatic acinar cells are dependent on Bax and can be reduced by Ca 2+-like peptides.
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