Product Name :
Nociceptin (1-7)
CAS NO. :
178249-42-8
Formula :
C31H41N7O9
Molecular Weight::
655.70
Target:
Opioid Receptor
Serial Number:
Phe-Gly-Gly-Phe-Thr-Gly-Ala
Short serial number :
FGGFTGA
Purity:
95%
Description :
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo.Nociceptin (1-7) acetate is a potent opioid receptor-like 1 (ORL1) receptor agonist, which in combination with nociceptin can reduce hyperalgesia and has antinociceptive activity.
References:
[1].T Sakurada, et al. Nociceptin (1 – 7) antagonizes nociceptin-induced hyperalgesia in mice.Br J Pharmacol. 1999 Nov;128(5):941-4.
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