Product Name :
PAR-2 Agonist
CAS NO. :
171436-38-7
Formula :
C29H56N10O7
Molecular Weight::
656.82
Target:
Protease Activated Receptor (PAR)
Serial Number:
Ser-Leu-Ile-Gly-Arg-Leu-NH2
Short serial number :
SLIGRL-NH2
Purity:
95%
Description :
SLIGRL-NH2 TFA (Protease-Activated Receptor-2 Activating Peptide TFA) is an agonist of Protease-Activated Receptor-2 (PAR-2).Agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2). Activates PAR2 (EC50 ~ 5 μM) and facilitates gastrointestinal transit in mice in vivo. Control peptide LRGILS-NH2 also available.
References:
[1].Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms. [2].Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlative responses of lumbar dorsal horn neurons in the mouse.
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