Product Name :
Protease-Activated Receptor 1 (PAR1) Agonist
CAS NO. :
197794-83-5
Formula :
C31H53N9O6
Molecular Weight::
647.81
Target:
Protease Activated Receptor (PAR)
Serial Number:
Thr-Phe-Leu-Leu-Arg-NH2
Short serial number :
TFLLR-NH2
Purity:
95%
Description :
TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.TFLLR-NH2 2TFA, derived from the protease-activated receptor-1 (PAR1), is a selective PAR1 agonist with an EC50 of 1.9 μM.
References:
[1].Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. [2].Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. [3]. Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620.
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