ThrombinReceptorActivatorfor Peptide 6(TRAP-6) | DNA

Product Name :
ThrombinReceptorActivatorfor Peptide 6(TRAP-6)

CAS NO. :
141136-83-6

Formula :
C34H56N10O9

Molecular Weight::
748.87

Target:
Protease Activated Receptor (PAR)

Serial Number:
Ser-Phe-Leu-Leu-Arg-Asn

Short serial number :
SFLLRN

Purity:
95%

Description :
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4.Peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. Stimulates platelet aggregation (EC50 = 0.8 μM), promotes intracellular Ca2+ mobilization and induces rapid phosphodiesterase 3A (PDE3A) phosphorylation.

References:
[1].Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin. [2].Disparate effects of thrombin receptor activating peptide on platelets and peripheral vasculature in rats.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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