Product Name :
PAR-2 (6-1) amide (human)
CAS NO. :
942413-05-0
Formula :
C28H54N8O7
Molecular Weight::
614.78
Target:
Protease Activated Receptor (PAR)
Serial Number:
Val-Lys-Gly-Ile-Leu-Ser-NH2
Short serial number :
VKGILS-NH2
Purity:
95%
Description :
VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells.
References:
[1].M Tognetto, et al. Evidence That PAR-1 and PAR-2 Mediate Prostanoid-Dependent Contraction in Isolated Guinea-Pig Gallbladder. Br J Pharmacol. 2000 Oct;131(4):689-94. [2].David A Vesey, et al. Proinflammatory and Proliferative Responses of Human Proximal Tubule Cells to PAR-2 Activation. Am J Physiol Renal Physiol. 2007 Nov;293(5):F1441-9.
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