Ac-RYYRWK-NH2 | DNA_ Alkylatingdna-alkylating.com

Product Name :
Ac-RYYRWK-NH2

CAS NO. :
408305-09-9

Formula :
C49H69O9N15

Molecular Weight::
1012.17

Target:
Opioid Receptor

Serial Number:
Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-NH2

Short serial number :
Ac-RYYRWK-NH2

Purity:
95%

Description :
Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors.Ac-RYYRWK-NH2 acetate is a potent and selective partial agonist of the nociceptin receptor (NOP), which is the endogenous ORL1 receptor agonist.

References:
[1].C T Dooley, et al. Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1.J Pharmacol Exp Ther. 1997 Nov;283(2):735-41. [2].M Ho, et al, Characterization of the ORL(1) receptor on adrenergic nerves in the rat anococcygeus muscle. Br J Pharmacol. 2000 Sep;131(2):349-55.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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