Product Name :
[Lys1015, 1024]-Thrombospondin-1(1015-1024), human
CAS NO. :
178921-95-4
Formula :
C68H105N17O12S1
Molecular Weight::
1384.73
Target:
Others
Serial Number:
Lys-Arg-Phe-Tyr-Val-Val-Met-Trp-Lys-Lys-OH
Short serial number :
KRFYVVMWKK
Purity:
95%
Description :
Integrin-associated protein (IAP/CD47) agonist peptide, 4N1K (KRFYVVMWKK), derived from the cell binding domain of thrombospondin-1 (TS1). The peptide has been shown to stimulate integrin-dependent cell functions, including platelet aggregation.
References:
[1]. Involvement of a CD47-dependent pathway in platelet adhesion on inflamed vascular endothelium under flow. [2]. Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain. [3]. The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells.
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