Product Name: PF-06840003
Chemical Name: 3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
SMILES Code: C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F
CAS NO: 83207-58-3 Product: 4-Azido-L-phenylalanine
Synonym: PF06840003; PF 06840003
Chemical Formula: C12H9FN2O2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).MAPKAPK2 MK2) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor. PF-06840003 reverses IDO-1-induced T-cell anergy in vitro, which reduces intratumoral kynurenine levels in mice by >80% and inhibits tumor growth in multiple preclinical syngeneic mPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19486511
