Product Name: SLx-2119
Chemical Name: 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide
SMILES Code: O=C(NC(C)C)COC1=CC=CC(C2=NC(NC3=CC4=C(NN=C4)C=C3)=C5C=CC=CC5=N2)=C1
CAS NO: 63238-67-5 Product: Z-Ile-Leu-aldehyde
Synonym: SLx 2119; SLx2119; ROCK inhibitor; KD-025
Chemical Formula: C26H24N6O2
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).ERK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: SLx-2119 (KD-025) is a small molecule and selective inhibitor of ROCK2. SLx-2119 selectively inhibits activity of human ROCK2 (IC50 = 105 nM), while effects on human ROCK1 in this cell-free system were minimal (IC50 = 24 μM) in vitro.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17322921
