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Product Name :
Magainin 1

CAS NO. :
108433-99-4

Formula :
C112H177N29O28S

Molecular Weight::
2409.9

Target:
Bacterial; Antibiotic; Fungal

Serial Number:
Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser

Short serial number :
GIGKFLHSAGKFGKAFVGEIMKS

Purity:
≥95%

Description :
Magainins are peptide antibiotics with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. Magainin 1 and 2 are closely related peptides of 23 amino acids each and differ by two substitutions. These antimicrobial peptides have broad-spectrum, non-specific activity against a wide range of micro-organisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeasts and fungi, and may also be hemolytic and cytotoxic to cancer cells. Magainin 1 is a bactericide. Both Magainin 1 and 2 exhibit inhibitory action toward Herpes simplex virus type 1(HSV-1) and HSV-2.

References:
[1].Williams, RW. et al. Biophysical J. 53, 631A (1988); [2]. Morvan, A. et al. Mol. Mar. Biol. Biotechnol. 3, 327 (1994); [3].Matanic, A. et al. Int. J. Antimicrob Agents 23, 382 (2004); [4].Zasloff, M. Proc. Natl. Acad. Sci. 84, 5449 (1987).

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna