HJ Inhibitor Peptide 2 | DNA_ Alkylatingdna-alkylating.com

Product Name :
HJ Inhibitor Peptide 2

CAS NO. :

Formula :
C48H61N13O7S

Molecular Weight::
964.16

Target:

Serial Number:
Lys-Trp-Trp-Cys-Arg-Trp

Short serial number :
KWWCRW

Purity:
≥95%

Description :
This peptide traps the protein-bound Holliday junctions (HJ) intermediate and preventing its resolution either to substrates or to products, thus inhibiting recombination. HJ intermediates arise in several central pathways of DNA repair, replication fork restart, and site-specific recombination catalysed by tyrosine recombinases.

References:
[1].Kepple, K. et al., Proc. Natl. Acad. Sci. USA, 102, 6867 (2005); Gunderson, C.; Segall, A., Mol. Microbio., 59, 1129 (2006).

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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