Product Name :
PD-1/PD-L1 Inhibitor 3
CAS NO. :
1629654-95-0
Formula :
C89H126N24O18S
Molecular Weight::
1852.17
Target:
PD-1/PD-L1
Serial Number:
Maa-Phe-Ala-Asn-Pro-His-Leu-Sar-Trp-Ser-Trp-Nle-Nle-Arg-Cys-Gly (Disulfide bridge: Maa1-Cys15
Short serial number :
Maa-FANPHL-Sar-WSW-Nle-Nle-RCG (Disulfide bridge: Maa1-Cys15
Purity:
95%
Description :
PD-1/PD-L1-IN 3, a macrocyclic peptide, is a potent and selective inhibitor of the PD-1/PD-L1 and CD80/PD-L1 interactions extracted from patent WO2014151634A1, compound No.1. PD-1/PD-L1-IN 3 interferes with PD-L1 binding to PD-1 and CD80 by binding to PD-L1, with IC50s of 5.60 nM and 7.04 nM, respectively. PD-1/PD-L1-IN 3 can be used for the research of various diseases, including cancer and infectious diseases.
References:
[1]. MILLER, Michael Matthew, et al. Macrocyclic inhibitors of the pd-1/pd-l1 and cd80(b7-1)/pd-l1 protein/protein interactions. WO2014151634A1.
Related websites: https://www.medchemexpress.com/antibodies.html
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