Product Name: OICR-9429
Chemical Name: N-(4-(4-methylpiperazin-1-yl)-3′-(morpholinomethyl)-[1,1′-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide
SMILES Code: O=C(C(C(C(F)(F)F)=C1)=CNC1=O)NC2=CC(C3=CC=CC(CN4CCOCC4)=C3)=CC=C2N5CCN(C)CC5
CAS NO: 72873-74-6 Product: Peimine
Synonym: OICR9429; OICR 9429
Chemical Formula: C29H32F3N5O3
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Histone Demethylase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50 of 5 uM. inhibit proliferation and induce differentiation. OICR-9429 selectively inhibited proliferation and induced differentiation in p30-expressing human AML cells. OIPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21777194
