MeOSuc-AAPA-CMK | DNA_ Alkylatingdna-alkylating.com

Product Name :
MeOSuc-AAPA-CMK

CAS NO. :
111682-13-4

Formula :
C20H31O8N4l1

Molecular Weight::
455.48

Target:
Protease Activated Receptor (PAR)

Serial Number:
MeOSuc-Ala-Ala-Pro-Ala-CMK

Short serial number :
MeOSuc-AAPA-CMK

Purity:
95%

Description :
MeOSuc-AAPA-CMK, inhibitor of human neutrophil elastase. The structure of the enzyme-inhibitor complex at 1.84 Å resolution reveals crosslinking of the catalytic residues His-57 and Ser-195 by the peptidyl chloromethylketone.

References:
[1]. Monoclonal LYM-1 antibody-dependent cytolysis by human neutrophils exposed to GM-CSF: auto-regulation of target cell attack by cathepsin G. [2]. Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution. [3]. A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine protease.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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