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Product Name: UNC0379
Chemical Name: 6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine
SMILES Code: COC1=C(OC)C=C(N=C(N2CCCC2)N=C3NCCCCCN4CCCC4)C3=C1
CAS NO: 299-75-2 Product: Bufalin
Synonym: UNC-0379; UNC 0379
Chemical Formula: C23H35N5O2Molecular Weight: 413.5563
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Apoptosis inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: UNC0379 is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8. UNC0379 is active in multiple biochemical assays. Its affinity to SETD8 was confirmed by ITC (isothermal titration calorimetry) and SPR (surface plasmon resonanPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21508362

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Author: DNA_ Alkylatingdna