Product Name :
GOAT-IN-1
Description:
GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.
CAS:
1452473-54-9
Molecular Weight:
415.81
Formula:
C18H13ClF3NO3S
Chemical Name:
2-(4-chloro-6-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]methoxy-1-benzothiophen-3-yl)acetic acid
Smiles :
CC1=NC(=CC=C1COC1=CC2SC=C(CC(O)=O)C=2C(Cl)=C1)C(F)(F)F
InChiKey:
IXAAPJMGWLXOIL-UHFFFAOYSA-N
InChi :
InChI=1S/C18H13ClF3NO3S/c1-9-10(2-3-15(23-9)18(20,21)22)7-26-12-5-13(19)17-11(4-16(24)25)8-27-14(17)6-12/h2-3,5-6,8H,4,7H2,1H3,(H,24,25)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Hesperetin custom synthesis
Shelf Life:
≥12 months if stored properly.24(S)-Hydroxycholesterol Neuronal Signaling
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer’s disease, Parkinson’s disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.|Product information|CAS Number: 1452473-54-9|Molecular Weight: 415.81|Formula: C18H13ClF3NO3S|Chemical Name: 2-(4-chloro-6-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]methoxy-1-benzothiophen-3-yl)acetic acid|Smiles: CC1=NC(=CC=C1COC1=CC2SC=C(CC(O)=O)C=2C(Cl)=C1)C(F)(F)F|InChiKey: IXAAPJMGWLXOIL-UHFFFAOYSA-N|InChi: InChI=1S/C18H13ClF3NO3S/c1-9-10(2-3-15(23-9)18(20,21)22)7-26-12-5-13(19)17-11(4-16(24)25)8-27-14(17)6-12/h2-3,5-6,8H,4,7H2,1H3,(H,24,25)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32726814 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM.|Products are for research use only. Not for human use.|
