Product Name :
cyt-PTPε Inhibitor-1
Description:
cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity.
CAS:
428478-94-8
Molecular Weight:
368.45
Formula:
C19H20N4O2S
Chemical Name:
3-5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl-1-(4-methylphenyl)urea
Smiles :
CC1C=C(C)C(=CC=1)OCC1=NN=C(NC(=O)NC2C=CC(C)=CC=2)S1
InChiKey:
QUSAMXSWOZSTRQ-UHFFFAOYSA-N
InChi :
InChI=1S/C19H20N4O2S/c1-12-4-7-15(8-5-12)20-18(24)21-19-23-22-17(26-19)11-25-16-9-6-13(2)10-14(16)3/h4-10H,11H2,1-3H3,(H2,20,21,23,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity.|Product information|CAS Number: 428478-94-8|Molecular Weight: 368.45|Formula: C19H20N4O2S|Chemical Name: 3-5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl-1-(4-methylphenyl)urea|Smiles: CC1C=C(C)C(=CC=1)OCC1=NN=C(NC(=O)NC2C=CC(C)=CC=2)S1|InChiKey: QUSAMXSWOZSTRQ-UHFFFAOYSA-N|InChi: InChI=1S/C19H20N4O2S/c1-12-4-7-15(8-5-12)20-18(24)21-19-23-22-17(26-19)11-25-16-9-6-13(2)10-14(16)3/h4-10H,11H2,1-3H3,(H2,20,21,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Tetracycline supplier |Shelf Life: ≥12 months if stored properly.Perifosine Activator |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33075236 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|cyt-PTPε Inhibitor-1 (Compound 62) is a potent cytosolic protein tyrosine phosphatase epsilon with anti-osteoclastic activity.|References:| Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211. Products are for research use only. Not for human use.|