Product Name :
SIRT2 (human), (recombinant) (His-tag)
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43 kDa
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Description:
Due to their roles in gene silencing, aging, and oxidative stress responses, it is believed that sirtuins (NAD-dependent lysine deacetylases) play a crucial role in cell metabolism.2138440-82-9 References Human SIRT2 is a class I sirtuin, although not as closely related to Sir2 and human SIRT1. Its catalytic core has the same basic two-domain architecture and central groove as other sirtuins and an interaction with the homeobox transcription factor HOXA10.
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| Alternative Name Sirtuin 2 | Formulation Liquid.2244684-50-0 manufacturer In 25mM TRIS, pH 7.PMID:29261944 5, containing 100mM NaCl, 5mM DTT and 10% glycerol. | MW 43 kDa | Purity Detail Purified by multi-step chromatography. | Source Produced in E. coli. Contains a N-terminal His-tag. | Specific Activity One unit will deacetylate 1pmol/min of FLUOR DE LYS®-SIRT2 substrate . | UniProt ID Q8IXJ6