Product Name :
Incensole Acetate
Description:
Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs.
CAS:
34701-53-6
Molecular Weight:
348.52
Formula:
C22H36O3
Chemical Name:
(1R, 2S, 12S)-1, 5, 9-trimethyl-12-(propan-2-yl)-15-oxabicyclo[10.2.1]pentadeca-5, 9-dien-2-yl acetate
Smiles :
C[C@@]12CC[C@@](CC=C(C)CCC=C(C)CC[C@@H]1OC(C)=O)(O2)C(C)C |c:6,11|
InChiKey:
HVBACKJYWZTKCA-FZMWDMPZSA-N
InChi :
InChI=1S/C22H36O3/c1-16(2)22-13-12-18(4)9-7-8-17(3)10-11-20(24-19(5)23)21(6,25-22)14-15-22/h8,12,16,20H,7,9-11,13-15H2,1-6H3/b17-8-,18-12-/t20-,21+,22+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury.Crizanlizumab Immunology/Inflammation Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs.|Product information|CAS Number: 34701-53-6|Molecular Weight: 348.Cynarin site 52|Formula: C22H36O3|Chemical Name: (1R, 2S, 12S)-1, 5, 9-trimethyl-12-(propan-2-yl)-15-oxabicyclo[10.PMID:32439217 2.1]pentadeca-5, 9-dien-2-yl acetate|Smiles: C[C@@]12CC[C@@](CC=C(C)CCC=C(C)CC[C@@H]1OC(C)=O)(O2)C(C)C |c:6,11||InChiKey: HVBACKJYWZTKCA-FZMWDMPZSA-N|InChi: InChI=1S/C22H36O3/c1-16(2)22-13-12-18(4)9-7-8-17(3)10-11-20(24-19(5)23)21(6,25-22)14-15-22/h8,12,16,20H,7,9-11,13-15H2,1-6H3/b17-8-,18-12-/t20-,21+,22+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25–35-induced cell death, a 48–52% decrease in cell viability at Aβ25–35 is restored to 85–89% upon pre-treatment with IA. Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25–35 in hOBNSCs.|References:|El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.Products are for research use only. Not for human use.|
