Product Name :
(Val³⁴)-Amyloid β-Protein (1-40)
CAS NO. :
1678415-83-2
Formula :
C193H293N53O58S1
Molecular Weight::
4315.78
Target:
Serial Number:
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Val-Met-Val-Gly-Gly-Val-Val
Short serial number :
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGVMVGGVV
Purity:
95%
Description :
Cerebral amyloid angiopathy (CAA) is a common finding in Alzheimer’s disease in which amyloid-Aβ vascular deposits are featured in >80% of the cases. Mutations in the positions 21-23 (e.g. Dutch mutation E22Q) are primarily associated with CAA, although they manifest with strikingly different clinical phenotypes: cerebral hemorrhage or dementia. The Piedmont L34V Aβ mutant, located outside this hot spot, shows a similar hemorrhagic phenotype, albeit less aggressive than the widely studied Dutch variant.
References:
[1]. A novel AbetaPP mutation exclusively associated with cerebral amyloid angiopathy. [2].Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
CTX-471 Biological Activity
Hexokinase I (YP6080) Mouse mAb Purity & Documentation
Hsp90 beta Antibody: Hsp90 beta Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Hsp90 beta. It can be used for WB,ICC/IF,IHC-P,IP,FC assays with tag free, in the background of Human, Mouse, Rat.
