Product Name :
(Gln²²)-Amyloid β-Protein (1-42)
CAS NO. :
147335-12-4
Formula :
C203H312N56O59S1
Molecular Weight::
4513.05
Target:
Amyloid-β
Serial Number:
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gln-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Short serial number :
DAEFRHDSGYEVHHQKLVFFAQDVGSNKGAIIGLMVGGVVIA
Purity:
95%
Description :
The Dutch mutation (E22Q) aggregates more readily than the wild-type sequence. The resulting fibrils show increased neurotoxicity.
References:
[1]. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. [2]. Effect of pathogenic mutations on the structure and dynamics of Alzheimer’s A beta 42-amyloid oligomers. [3].Mutation-based structural modification and dynamics study of amyloid beta peptide (1-42): An in-silico-based analysis to cognize the mechanism of aggregation.
Related websites: https://www.medchemexpress.com/antibodies.html
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