Product Name :
α-Synuclein (71-82) (human)
CAS NO. :
332867-16-0
Formula :
C51H92N14O17
Molecular Weight::
1173.36
Target:
α-synuclein
Serial Number:
Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val
Short serial number :
VTGVTAVAQKTV
Purity:
95%
Description :
The deposition of α-synuclein (α-syn) fibrils in Lewy bodies is a characteristic feature of individuals with neurodegenerative disorders. The central hydrophobic region of α-synuclein, resembled by the peptide α-synuclein (71-82), is believed to be responsible for the protein aggregation. In addition, α-synuclein (71-82) forms amyloid fibrils of similar morphology to α-synuclein, suggesting that this region contributes to the fibrillogenic core of the full-length protein, referring to the studies of Madine and coworkers.
References:
[1].Studies of the aggregation of an amyloidogenic alpha-synuclein peptide fragment. [2].Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation.
Related websites: https://www.medchemexpress.com/antibodies.html
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