Mca-Amyloid β/A4 Protein Precursor₇₇₀ (667-676)

Product Name :
Mca-Amyloid β/A4 Protein Precursor₇₇₀ (667-676)

CAS NO. :
1802078-33-6

Formula :
C87H129O28N27S1

Molecular Weight::
2033.18

Target:
others

Serial Number:
MCA-Ser-Glu-Val-Lys-Met-Asp-Ala-Glu-Phe-Arg-Lys(Dnp)-Arg-Arg-NH2

Short serial number :
Mca-SEVKMDAEFR-K(Dnp)-RR-NH2

Purity:
95%

Description :
This fluorescent (FRET) peptide substrate contains the wild-type amyloid precursor protein (APP) β-secretase cleavage site. Mca-SEVKMDAEFRK(Dnp)RR- amide has been used for assaying β-secretase-like activity of thimet oligopeptidase (TOP, EC 3.4.24.15). The results suggested that TOP is a potential β-secretase candidate and is involved in the processing of APP in vivo.

References:
[1].Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein .

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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