Caspase 3 (Apopain) Inhibitor 1b | DNA_ Alkylatingdna-alkylating.com

Product Name :
Caspase 3 (Apopain) Inhibitor 1b

CAS NO. :
178603-73-1

Formula :
C28H42N6O12S1

Molecular Weight::
686.73

Target:
Caspase

Serial Number:
Biotinyl-Asp-Glu-Val-Asp-CHO

Short serial number :
Biotinyl-DEVD-CHO

Purity:
95%

Description :
This biotinylated apopain inhibitor has successfully been used for the affinity purification – on a streptavidin-agarose column – of caspase-3 (apopain), the enzyme that cleaves the poly(ADP-ribose) polymerase (PARP). Biotinyl-DEVD-CHO showed an inhibitory activity comparable to that of the N-acetylated analog inhibitor (H-2496) (IC₅₀ = 0.2 nM).

References:
[1]. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. [2].Probing the caspase-3 active site by fluorescence lifetime measurements

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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