Product Name :
Amyloid β-Protein (3-42)
CAS NO. :
157884-74-7
Formula :
C196H301N53O56S1
Molecular Weight::
4327.87
Target:
Amyloid-β
Serial Number:
Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Short serial number :
EFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Purity:
95%
Description :
The N-terminally truncated Aβ42 may be formed in increased amounts as AD progresses. Aβ 3-42 is the precursor of the Pyr-peptide. (Pyr³)-Aβ 3-42 positive plaques are resistant to age-dependent degradation likely due to their high stability and propensity to aggregate.
References:
[1]. The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42. [2]. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases. [3]. Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration.
Related websites: https://www.medchemexpress.com/antibodies.html
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