Z-LVG-CHN2 | DNA_ Alkylatingdna-alkylating.com

Product Name :
Z-LVG-CHN2

CAS NO. :
119670-30-3

Formula :
C22H31N5O5

Molecular Weight::
445.51

Target:
Cathepsin/HSV/SARS-CoV

Serial Number:
Z-Leu-Val-Gly-diazomethylketone

Short serial number :
Z-LVG-DMK

Purity:
95%

Description :
The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication.Irreversible inhibitor of streptopain.

References:
[1]. R L Mellgren, et al. Inhibition of growth of human TE2 and C-33A cells by the cell-permeant calpain inhibitor benzyloxycarbonyl-Leu-Leu-Tyr diazomethyl ketone. Exp Cell Res. 1994 Nov;215(1):164-71. [2]. L Björck, et al. Cystatin C, a human proteinase inhibitor, blocks replication of herpes simplex virus. J Virol [3]. Laura Riva, et al.A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals. bioRxiv. 2020 Apr 17;2020.04.16.044016.

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Author: DNA_ Alkylatingdna

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