Calpain Inhibitor III; Z-Val-Phe-CHO | DNA_ Alkylatingdna-alkylating.com

Product Name :
Calpain Inhibitor III; Z-Val-Phe-CHO

CAS NO. :
88191-84-8

Formula :
C22H26O4N2

Molecular Weight::
382.45

Target:
Proteasome

Serial Number:
Cbz-Val-Phe-CHO

Short serial number :
Z-VF-CHO

Purity:
95%

Description :
Application of the calpain inhibitor Z-VF-CHO reduced capsaicin-mediated cell death in cultured dorsal root ganglion neurons. Dong et al. observed that this inhibitor modulated Aβ formation by inhibiting the formation of intermediate Aβ 1-46 and protecting Aβ from degradation.

References:
[1]. Calpain inhibitor MDL28170 modulates Abeta formation by inhibiting the formation of intermediate Abeta46 and protecting Abeta from degradation. [2]. Changes in calcium dynamics following the reversal of the sodium-calcium exchanger have a key role in AMPA receptor-mediated neurodegeneration via calpain activation in hippocampal neurons [3]. Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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