Product Name :
Antennapedia Peptide, acid
CAS NO. :
188842-14-0
Formula :
C104H168N34O20S1
Molecular Weight::
2246.73
Target:
others
Serial Number:
Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH
Short serial number :
RQIKIWFQNRRMKWKK
Purity:
95%
Description :
Antennapedia Peptide, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptides.Antennapedia Peptide (43-58), acid, a cell-penetrating peptide corresponding to the region within the DNA binding domain of the Drosophila Antennapedia, is mapped to be responsible for cellular internalization. It is also known as penetratin and has been shown to be able to translocate through the plasma membrane to the cytosol and nucleus of living cells, both at 37°C and 4°C.
References:
[1]. Imesch P, et al. Conjugates of cytochrome c and antennapedia peptide activate apoptosis and inhibit proliferation of HeLa cancer cells. Exp Ther Med. 2013 Sep;6(3):786-790. Epub 2013 Jul 4. [2]. Du LQ, et al. Radiation-sensitising effects of antennapedia proteins (ANTP)-SmacN7 on tumour cells. Int J Mol Sci. 2013 Dec 11;14(12):24087-96.
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