Cortistatin 17, human | DNA_ Alkylatingdna-alkylating.com

Product Name :
Cortistatin 17, human

CAS NO. :
189450-19-9

Formula :
C96H139N27O24S3

Molecular Weight::
2151.54

Target:
others

Serial Number:
Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge Cys5-Cys16)

Short serial number :
DRMPCRNFFWKTFSSCK(Disulfide bridge Cys5-Cys16)

Purity:
≥95%

Description :
Cortistatin-17 shows structural similarities to somatostatin. The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin. Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14. Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat. It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms.

References:
[1].Convenient fluorometric assay for matrix metalloproteinase activity and its application in biological media.B.Beekman et al., FEBS Lett., 390, 221 (1996) [2].Identification and characterization of a novel human cortistatin-like peptide.S.Fukusumi et al., Biochem. Biophys. Res. Commun., 232, 157 (1997)

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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