Product Name :
Corticostatin-14
CAS NO. :
193829-96-8
Formula :
C81H113N19O19S2
Molecular Weight::
1721
Target:
Serial Number:
Pro-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: 2-13)
Short serial number :
PCKNFFWKTFSSCK( Disulfide bridge: 2-13)
Purity:
≥95%
Description :
Cortistatin 14 is an endogenous neuropeptide, mainly expressed in the cortex and hippocampus, that has structural and functional similarities to somatostatin-14. Cortistatin 14 displays potency at all somatostatin receptors (sst1 – sst5) and prevents somatostatin-14 binding (IC50 values are 0.09, 0.2, 0.3, 0.3 and 5 nM at sst2, sst4, sst3, sst5 and sst1 receptors, respectively). Also a potent MRGPRX2 agonist (EC50 = 25 nM in HEK293 cells) and binds to the growth hormone secretagog receptor (GHS-R1a). Exhibits neuronal depressant and sleep-modulating properties in vivo.
References:
Related websites: https://www.medchemexpress.com/antibodies.html
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