Share this post on:

Product Name :
Cholecystokinin Precursor (24-32) (rat)

CAS NO. :
99291-20-0

Formula :
C42H69N9O14S

Molecular Weight::
956.13

Target:
GCGR

Serial Number:
Val-Pro-Val-Glu-Ala-Val-Asp-Pro-Met

Short serial number :
VPVEAVDPM

Purity:
≥95%

Description :
Its mechanism of action is to act on pancreatic β cells, promote the synthesis and secretion of insulin, stimulate the proliferation and differentiation of pancreatic islet β cells, inhibit the apoptosis of pancreatic islet β cells, increase the number of pancreatic islet β cells, and have the effect of protecting the function of pancreatic islets. It can also act on pancreatic islet α cells, inhibit the release of glutina Chemicalbook, and reduce the release of liver glucose. It acts on pancreatic islet δ cells, promotes the secretion of somatostatin, and participates in the inhibition of glucagon secretion. Enhance insulin sensitivity, slow down gastric emptying, act on the hypothalamus to suppress appetite, reduce body weight, and achieve the effect of lowering blood sugar through these effects.

References:
[1]. Marso SP, et al. Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med. 2016 Nov 10;375(19):1834-1844. [2]. Zhang L, et al. Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson’s disease mouse model. Neuropeptides. 2018 Oct;71:70-80. [3]. Dhillon S, et al. Semaglutide: First Global Approval. Drugs. 2018 Feb;78(2):275-284.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Chk1 Rabbit mAb Epigenetic Reader Domain
C5b-9 Antibody medchemexpress
Phospho-p95/NBS1 (Ser343) Antibody: Phospho-p95/NBS1 (Ser343) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 85 kDa, targeting to Phospho-p95/NBS1 (S343). It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human, Mouse.

Share this post on:

Author: DNA_ Alkylatingdna