G3335 acetate | DNA_ Alkylatingdna-alkylating.com

Product Name :
G3335 acetate

CAS NO. :
36099-95-3

Formula :
C16H19N3O5

Molecular Weight::
333.34

Target:
PPAR

Serial Number:
Trp-Glu-OH

Short serial number :
WE

Purity:
95%

Description :
G3335 acetate is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd of 8.34 µM. G3335 reversibly and competitively blocks activation of PPARγ by rosiglitazone.Peroxisome proliferator-activated receptor γ (PPARγ) antagonist.G3335 is a cell-permeable dipeptide that selectively and reversibly antagonizes PPARγ with a Kd value of 8.34 µM. G3335 reversiblyand competitively blocks activation of PPARγ by rosiglitazone.

References:
[1]. Ye F, et al. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem. 2006 Jan;7(1):74-82.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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