Product Name :
[Lys0] – Bradykinin (Kallidin)
CAS NO. :
342-10-9
Formula :
C56H85N17O12
Molecular Weight::
1188.41
Target:
Bradykinin Receptor
Serial Number:
Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
Short serial number :
KRPPGFSPFR
Purity:
≥95%
Description :
Bradykinins (BK) and related kinins are potent inflammatory mediators produced during acute and chronic inflammation. The two main ‘kinins’ in mammals are the nonapeptide bradykinin, BK (1-9) and the decapeptide kallidin (KD), [Lys0]-BK(1-10). Their biological actions are mediated by two distinct receptors, termed B1 and B2. BK and [Lys0]-BK are peptides which are released at high nanomolar concentrations into the tear-film of ocular allergic patients.
References:
[1].Altamura, M. et al Regul. Pept. 80, 13 (1999); [2].Siebeck, M. et al. Immunopharmacol. 40, 49 (1998); [3]. Wiernas, T. et al. Br. J. Pharmacol. 121, 649 (1997).
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