Product Name :
NFF-2
CAS NO. :
158584-08-8
Formula :
C79H105O19N19S1
Molecular Weight::
1656.86
Target:
MMP
Serial Number:
MCA-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2
Short serial number :
Mca-RPKPYA-Nva-WM-K(Dnp)-NH2
Purity:
95%
Description :
The FRET substrate Mca-RPKPYA-Nva-WMK(Dnp)-amide was hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M⁻¹s⁻¹) than by interstitial collagenase (MMP-1). However, it showed little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M⁻¹s⁻¹), and gelatinase B (MMP-9) (kcat/Km= 55300 M⁻¹s⁻¹). Metalloelastase (MMP-12) digested this fluorogenic substrate with a kcat/Km of 243000 M⁻¹s⁻¹.
References:
Related websites: https://www.medchemexpress.com/antibodies.html
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