Product Name :
T-Peptide
CAS NO. :
2022956-62-1
Formula :
C92H171O18N45
Molecular Weight::
2195.63
Target:
HIV Microtubule/Tubulin
Serial Number:
Ac-DVal-DGln-DIle-DVal-DTyr-DLys-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2
Short serial number :
Ac-vqivykRRRRRRRRR-NH2
Purity:
95%
Description :
Highly neurotoxic cell-permeable analog of PHF6. Induces aggregation of Tau peptides.T-peptide, a highly neurotoxic cell-permeable analog of PHF6, can be used in the study of human immunodeficiency virus (HIV) infection. T-peptide can induce Tau peptide aggregation, prevent cellular immunosuppression, improve the survival rate of sepsis mice, and inhibit the growth of residual tumor cells after surgical resection.
References:
[1]. Simpson DM, et, al. Peptide T in the treatment of painful distal neuropathy associated with AIDS: results of a placebo-controlled trial. The Peptide T Neuropathy Study Group. Neurology. 1996 Nov;47(5):1254-9. [2]. Gao YL, et, al. Tuftsin-derived T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. Sci Rep. 2015 Nov 18;5:16725.
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